Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3462955 | 0.83 | ALDH1A1 (1.00) | ALDH1A1POLBPKMKMT2AMAPK1 | |
| SCHEMBL11840921 | 0.77 | ALDH1A1 (0.68) | ALDH1A1POLBPKMKMT2AMAPK1 | |
| SCHEMBL15688484 | 0.77 | NPC1 (0.56) | ALDH1A1PKMKMT2AKDM4EMEN1 | |
| SCHEMBL4827943 | 0.75 | ALDH1A1 (0.56) | ALDH1A1POLBPKMKMT2AMAPK1 | |
| SCHEMBL11903535 | 0.74 | DDB1 (0.65) | ALDH1A1POLBPKMKMT2AMAPK1 | |
| SCHEMBL11454909 | 0.72 | DDB1 (0.59) | ALDH1A1PKMDDB1CRBNMAPT | |
| SCHEMBL30597578 | 0.72 | POLB (1.00) | ALDH1A1POLBPKMKMT2AMAPK1 | |
| SCHEMBL14721792 | 0.71 | DPP7 (0.46) | ALDH1A1POLBKMT2AMAPK1MEN1 | |
| SCHEMBL7345968 | 0.70 | HTT (0.60) | ALDH1A1PKMKMT2ADDB1CRBN | |
| SCHEMBL10454044 | 0.70 | ALDH1A1 (0.55) | ALDH1A1KMT2ADDB1CRBNMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331515-A1 | INSCETICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |