SCHEMBL3462955

SCHEMBL3462955

O=C(NC1CCSC1=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
POLB P06746 1/20 0.80
KMT2A Q03164 2/20 0.76
MAPK1 P28482 2/20 0.76
PKM P14618 1/20 0.70
MEN1 O00255 1/20 0.65
NPSR1 Q6W5P4 1/20 0.64
HSD17B10 Q99714 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.59
GAA P10253 1/20 0.59
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30597578 0.89 POLB (1.00) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL30597589 0.85 POLB (0.82) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL1936056 0.83 ALDH1A1 (0.71) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL10511025 0.83 KMT2A (0.72) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL29419157 0.83 ALDH1A1 (0.70) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL20300606 0.82 ALDH1A1 (0.69) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL14830534 0.80 KMT2A (0.72) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL13634694 0.79 KMT2A (1.00) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL18619386 0.79 POLB (0.72) ALDH1A1POLBKMT2AMAPK1PKM
SCHEMBL30004213 0.78 ALDH1A1 (0.63) ALDH1A1POLBKMT2AMAPK1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020045541-A1 CHROMATOGRAPHY CARRIER JSR株式会社 2020-03-05 WO disclosed
US-7750129-B2 Process for the purification of antibodies GE HEALTHCARE BIO-SCIENCES AB (SE) 2010-07-06 US disclosed
US-7320755-B2 Method of preparing ligands for hydrophobic interaction chromatography GE HEALTHCARE BIO-SCIENCES AB (SE) 2008-01-22 US disclosed
US-20070167613-A1 Process for the purification of antibodies CYTIVA BIOPROCESS R&D AB (SE) 2007-07-19 US disclosed
EP-1718386-A1 A PROCESS FOR THE PURIFICATION OF ANTIBODIES GE Healthcare Bio-Sciences AB (SE) 2006-11-08 EP disclosed
WO-2005082483-A1 A PROCESS FOR THE PURIFICATION OF ANTIBODIES GE HEALTHCARE BIO-SCIENCES AB (SE) 2005-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167613-A1 Process for the purification of antibodies FCGR1A, FCGRT, CD47 ALDH1A1 2803/4885POLB 4008/4885KMT2A 1459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.