Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360314 | 0.89 | RORC (0.65) | RORCMRGPRX4 | |
| SCHEMBL19360436 | 0.89 | RORC (0.51) | RORCTTRRBP4IDH1EPHX2 | |
| SCHEMBL19360582 | 0.88 | RORC (0.54) | RORCP2RX7RBP4IDH1EPHX2 | |
| SCHEMBL19360540 | 0.84 | RORC (0.45) | RORCIDH1EPHX2SLC6A4L3MBTL1 | |
| SCHEMBL20822477 | 0.80 | RORC (0.52) | RORCP2RX7MRGPRX4EPHX2 | |
| SCHEMBL19360306 | 0.80 | RORC (0.65) | RORCP2RX7MRGPRX4EPHX2 | |
| SCHEMBL30076092 | 0.80 | RORC (0.45) | RORCTTREPHX2 | |
| SCHEMBL19360525 | 0.79 | RORC (0.68) | RORCEPHX2 | |
| SCHEMBL19360385 | 0.79 | RORC (0.85) | RORC | |
| SCHEMBL18440466 | 0.79 | IDH1 (0.49) | RORCIDH1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |