Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.65 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360581 | 0.89 | RORC (0.53) | RORCMRGPRX4 | |
| SCHEMBL19360312 | 0.89 | RORC (0.66) | RORCESRRAMRGPRX4TRPM8 | |
| SCHEMBL19360436 | 0.88 | RORC (0.51) | RORCPPARGC5AR1 | |
| SCHEMBL21929295 | 0.84 | RORC (0.53) | RORCESRRAPPARGPPARDPPARA | |
| SCHEMBL28302148 | 0.84 | RORC (0.49) | RORCMRGPRX4PPARGPPARDPPARA | |
| SCHEMBL19360540 | 0.81 | RORC (0.45) | RORCPPARGPPARDPPARA | |
| SCHEMBL22238330 | 0.81 | RORC (0.51) | RORCMRGPRX4PPARGPPARDPPARA | |
| SCHEMBL29465610 | 0.81 | RORC (0.64) | RORCMRGPRX4PPARGPOLQ | |
| SCHEMBL19360545 | 0.81 | RORC (0.64) | RORCMRGPRX4PPARGPOLQ | |
| SCHEMBL19360574 | 0.81 | RORC (0.65) | RORCMRGPRX4PPARGPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |