Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360625 | 0.86 | USP2 (0.39) | RORCMAOAKDM4EALDH1A1PRMT1 | |
| SCHEMBL19360400 | 0.77 | RORC (0.51) | RORC | |
| SCHEMBL19360402 | 0.77 | RORC (0.67) | RORC | |
| SCHEMBL19360613 | 0.76 | HRH3 (0.44) | MAOAKDM4EALDH1A1POLBGAA | |
| SCHEMBL18440688 | 0.74 | RORC (0.43) | PTGER4RORCKDM4EALDH1A1TSHR | |
| SCHEMBL19360626 | 0.71 | L3MBTL1 (0.38) | RORC | |
| SCHEMBL10272098 | 0.70 | HRH3 (0.47) | KDM4EALDH1A1LMNA | |
| SCHEMBL4728865 | 0.67 | ATM (0.55) | PTGER4RORCMAOAKDM4EALDH1A1 | |
| SCHEMBL1779783 | 0.66 | ESR2 (0.47) | MAOAALDH1A1FDFT1LMNA | |
| SCHEMBL1782299 | 0.66 | ESR2 (0.47) | MAOAALDH1A1FDFT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |