Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797800 | 0.82 | MMP2 (0.43) | HRH3MMP2MMP13ALDH1A1MEN1 | |
| SCHEMBL29654096 | 0.82 | MMP2 (0.43) | HRH3MMP2MMP13ALDH1A1MEN1 | |
| SCHEMBL19360625 | 0.77 | USP2 (0.39) | MAOAALDH1A1MAPK1KDM4E | |
| SCHEMBL29654185 | 0.74 | HRH3 (0.59) | HRH3MMP2MMP13ALDH1A1MEN1 | |
| SCHEMBL5793708 | 0.74 | KDM4E (0.57) | HRH3ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL18440835 | 0.73 | KDM4E (0.41) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7920888 | 0.72 | ALDH1A1 (0.68) | HRH3MMP2MMP13ALDH1A1MEN1 | |
| SCHEMBL10272098 | 0.72 | HRH3 (0.47) | HRH3ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL18440581 | 0.72 | HRH3 (0.48) | HRH3MAOBMMP2MMP13ALDH1A1 | |
| SCHEMBL21985665 | 0.70 | KDM4E (0.47) | HRH3MMP2MMP13ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |