Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565510 | 0.89 | RAB9A (0.71) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL940111 | 0.87 | RAB9A (0.61) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL10205641 | 0.87 | RAB9A (0.61) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL1903659 | 0.86 | CYP4F2 (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL8112075 | 0.84 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL14349951 | 0.84 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL5561966 | 0.84 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL6404645 | 0.83 | NPC1 (0.54) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL29892760 | 0.83 | RAB9A (0.67) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9146676 | 0.83 | LMNA (0.68) | RAB9ANPC1HPGDCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958506-B | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH | 诺华股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2331518-A1 | NEW BRADYKININ B1 ANTAGONISTS | Evotec AG (DE) | 2011-06-15 | — | — | EP | disclosed |