Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565510 | 0.90 | RAB9A (0.71) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL940111 | 0.89 | RAB9A (0.61) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL11338386 | 0.89 | RAB9A (0.57) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL7565512 | 0.89 | RAB9A (0.70) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL1936080 | 0.87 | RAB9A (0.59) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL14349951 | 0.86 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL8112075 | 0.86 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL5561966 | 0.86 | RAB9A (0.58) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL29322953 | 0.86 | RAB9A (0.54) | RAB9ANPC1HPGDCRHBPCRHR2 | |
| SCHEMBL7472487 | 0.86 | SMN1; SMN2 (0.67) | RAB9ANPC1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168077-A1 | PHENOL-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE | CONAGEN INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-3774986-A1 | BRUSH PRODRUGS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3755325-A1 | SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| EP-3649135-A1 | SYNTHESIS OF HALICHONDRINS | President and Fellows of Harvard College (US) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019200367-A9 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-12-19 | — | — | WO | disclosed |
| WO-2019200367-A1 | BRUSH PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2019165229-A1 | SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| WO-2019010363-A1 | SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |
| US-20120077805-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | US | disclosed |
| US-7994313-B2 | Unsolvated benzodiazepine compositions and methods | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090275099-A1 | Methods and compositions for treating diseases and conditions associated with mitochondrial function | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090253686-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-10-08 | — | — | US | disclosed |
| US-20080293700-A1 | Compositions and Methods Relating to Novel Compounds and Targets Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293700-A1 | Compositions and Methods Relating to Novel Compounds and Targets Thereof | BAX, BAD, GABRB3 | RAB9A 3842/4885NPC1 1895/4885HPGD 1422/4885 |
| US-20090275099-A1 | Methods and compositions for treating diseases and conditions associated with mitochondrial function | ATP5F1A, ATP5MF, MT-ATP6 | RAB9A 2138/4885NPC1 1087/4885HPGD 625/4885 |
| US-20120077805-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | GABRA5, GABRA3, GABRA6 | RAB9A 2811/4885NPC1 302/4885HPGD 1215/4885 |
| US-20090253686-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | GABRA5, GABRA3, GABRA6 | RAB9A 2811/4885NPC1 302/4885HPGD 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.