Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216284 | 0.86 | GABRA2 (0.33) | GABRA2GABRB2CYP19A1 | |
| SCHEMBL11954946 | 0.84 | NOTUM (0.43) | MAOANOTUM | |
| SCHEMBL14212090 | 0.84 | GABRA2 (0.38) | GABRA2GABRB2CYP19A1NOTUM | |
| SCHEMBL14900333 | 0.83 | CYP4F2 (0.31) | — | |
| SCHEMBL15222209 | 0.82 | GABRA2 (0.45) | GABRA2GABRB2CYP19A1 | |
| SCHEMBL14212094 | 0.81 | NOTUM (0.41) | GABRA2GABRB2CYP19A1NOTUM | |
| SCHEMBL18767836 | 0.78 | GABRA2 (0.49) | HRH4HRH3GABRA2GABRB2CYP19A1 | |
| SCHEMBL20812235 | 0.78 | NOTUM (0.44) | GABRA2GABRB2CYP19A1NOTUM | |
| SCHEMBL11955225 | 0.78 | GABRA2 (0.31) | GABRA2GABRB2 | |
| SCHEMBL23451216 | 0.77 | GABRA2 (0.36) | GABRA2GABRB2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20180051041-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | THE MEDICINES COMPANY (SAN DIEGO), LLC | 2018-02-22 | — | — | US | disclosed |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CYP2C9 3416/4885TSHR 3677/4885CYP2C19 2911/4885 |
| US-20180051041-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | BCL6B, BTD, BCL6 | CYP2C9 2400/4885TSHR 1972/4885CYP2C19 1809/4885 |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | BTD, BCL6B, BPGM | CYP2C9 2757/4885TSHR 1897/4885CYP2C19 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.