Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966994 | 0.94 | USP2 (0.41) | USP2MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7979203 | 0.93 | MAPK1 (0.40) | USP2MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7979242 | 0.89 | L3MBTL1 (0.38) | USP2MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7966894 | 0.87 | SMN1; SMN2 (0.39) | USP2MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7978878 | 0.87 | MEN1 (0.38) | USP2ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL194662 | 0.85 | USP2 (0.47) | USP2MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL7095466 | 0.85 | USP2 (0.36) | USP2MAPK1 | |
| SCHEMBL7664876 | 0.83 | ADORA1 (0.34) | USP2ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL7665387 | 0.82 | ALDH1A1 (0.33) | USP2ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL7980615 | 0.81 | PDE5A (0.39) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105670-A1 | FUNGICIDAL MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-29 | — | — | US | claimed |
| EP-2086319-A1 | FUNGICIDAL MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-08-12 | — | — | EP | claimed |
| WO-2008060611-A1 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-22 | — | — | WO | claimed |
| EP-1511380-B1 | MIXTURES OF FUSED PYRIMIDINONES AND DINITROPHENOLIC COMPOUNDS USEFUL FOR CONTROLLING POWDERY MILDEWS | DU PONT (US) | 2006-10-18 | — | — | EP | claimed |
| US-20050239805-A1 | Mixtures of fused pyrimidinones and dinitrophenolic compounds useful for controlling powdery mildews | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-27 | — | — | US | claimed |
| EP-0888359-B1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-02 | — | — | EP | claimed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | claimed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | claimed |
| EP-3529246-B1 | OXADIAZOLES HAVING FUNGICIDAL ACTIVITY | FMC CORP (US) | 2023-10-18 | — | — | EP | disclosed |
| US-10448639-B2 | Fungicidal pyrazoles | FMC CORPORATION (US) | 2019-10-22 | — | — | US | disclosed |
| EP-3529246-A1 | FUNGICIDAL OXADIAZOLES | FMC Corporation (US) | 2019-08-28 | — | — | EP | disclosed |
| WO-2018080859-A1 | FUNGICIDAL OXADIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-03 | — | — | WO | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| EP-3239137-A1 | (5R)-4,5-DIHYDRO-ISOXAZOLE DERIVATIVES AS WELL AS 1-(2-CHLOROACETYL)-4-PIPERIDINE-CARBONITRILE AND -CARBOXAMIDE DERIVATIVES AS INTERMEDIATES IN THE PREPARATION OF E.G. 4-[4-[(5R)-4,5-DIHYDRO-ISOXAZOL-3-YL]-THIAZOL-2-YL]-PIPERIDINE DERIVATIVES AS FUNGICIDES FOR CROP PROTECTION | E. I. du Pont de Nemours and Company (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-1087939-A1 | PROCESS FOR PREPARATION OF PYRIMIDINONE DERIVATIVES | Syngenta Participations AG (CH) | 2001-04-04 | — | — | EP | disclosed |
| EP-1053229-A1 | CONDENSED 4-THIOXOPYRIMIDINE DERIVATIVES AS MICROBICIDES | Novartis AG (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999067202-A1 | PROCESS FOR PREPARATION OF PYRIMIDINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG . (CH) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999040074-A1 | CONDENSED 4-THIOXOPYRIMIDINE DERIVATIVES AS MICROBICIDES | NOVARTIS AG (CH) | 1999-08-12 | — | — | WO | disclosed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105670-A1 | FUNGICIDAL MIXTURES | DEGS1, GMDS, Q6ZSR9 | USP2 3188/4885MAPK1 2257/4885ALDH1A1 988/4885 |
| US-10448639-B2 | Fungicidal pyrazoles | CBR3, CBR1, CYP2S1 | USP2 4390/4885MAPK1 2750/4885ALDH1A1 2185/4885 |
| US-20050239805-A1 | Mixtures of fused pyrimidinones and dinitrophenolic compounds useful for controlling powdery mildews | CBR3, CBR1, C9 | USP2 4370/4885MAPK1 2860/4885ALDH1A1 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.