Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | DNM2 | P50570 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 3/20 | 0.31 |
| ▸ | CLK3 | P49761 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17562434 | 0.86 | NOS2 (0.43) | NOS2FLT3MAP4K4DNM2CLK2 | |
| SCHEMBL18474534 | 0.74 | NOS2 (0.53) | NOS2MAP4K4DNM2CYP2C19 | |
| SCHEMBL10244133 | 0.74 | USP2 (0.44) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL10244197 | 0.74 | USP2 (0.44) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL15445117 | 0.74 | USP2 (0.44) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL17573454 | 0.74 | NOS2 (0.56) | NOS2MAP4K4DNM2CYP2C19 | |
| SCHEMBL18483348 | 0.72 | NOS2 (0.45) | NOS2MAP4K4DNM2CYP2C19 | |
| SCHEMBL15301101 | 0.72 | NOS2 (0.45) | NOS2FLT3MAP4K4DNM2CYP2C19 | |
| SCHEMBL18485039 | 0.72 | NOS2 (0.51) | NOS2MAP4K4DNM2CLK2CLK3 | |
| SCHEMBL22526148 | 0.69 | ALDH1A1 (0.40) | USP2ALDH1A1GAAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9763951-B2 | 3-(3H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-09-19 | — | — | US | disclosed |