Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL4342322 | 1.00 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| Lithium Ion SCHEMBL193641 | 1.00 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL11600944 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL4339905 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL6436967 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL6439767 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL3002303 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL2138985 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL1565614 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A | |
| SCHEMBL2997852 | 0.95 | PPARG (0.52) | PPARGLMNANFE2L2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031798-B1 | A novel cross-linker for the preparation of a new family of single ion conduction polymers for electrochemical devices and such polymers | BELENOS CLEAN POWER HOLDING AG (CH) | 2017-09-27 | — | — | EP | disclosed |
| US-9771319-B2 | Cross-linker for the preparation of a new family of single ion conduction polymers for electrochemical devices and such polymers | BELENOS CLEAN POWER HOLDING AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-20160168086-A1 | NOVEL CROSS-LINKER FOR THE PREPARATION OF A NEW FAMILY OF SINGLE ION CONDUCTION POLYMERS FOR ELECTROCHEMICAL DEVICES AND SUCH POLYMERS | BELENOS CLEAN POWER HOLDING AG (CH) | 2016-06-16 | — | — | US | disclosed |
| EP-3031798-A1 | A novel cross-linker for the preparation of a new family of single ion conduction polymers for electrochemical devices and such polymers | Belenos Clean Power Holding AG (CH) | 2016-06-15 | — | — | EP | disclosed |
| US-8786932-B2 | Advanced electrode structures and electrochromic devices | NTERA, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8511841-B2 | Vehicular blind spot indicator mirror | DONNELLY CORPORATION (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120038967-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | NTERA LIMITED (IE) | 2012-02-16 | — | — | US | disclosed |
| EP-2401650-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | Ntera, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| US-20110128137-A1 | VEHICULAR BLIND SPOT INDICATOR MIRROR | DONNELLY CORPORATION (US) | 2011-06-02 | — | — | US | disclosed |
| US-7871169-B2 | Vehicular signal mirror | DONNELLY CORPORATION (US) | 2011-01-18 | — | — | US | disclosed |
| EP-1224505-A1 | ELECTROCHROMIC DEVICE | UNIVERSITY COLLEGE DUBLIN (IE) | 2002-07-24 | — | — | EP | disclosed |
| US-20020041443-A1 | Electrochromic mirrors and devices | VARAPRASAD DESARAJU V (US) | 2002-04-11 | — | — | US | disclosed |
| EP-0758929-B1 | ELECTROCHROMIC MIRRORS AND DEVICES | DONNELLY CORP (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-1152285-A2 | Electrochromic mirrors and devices | DONNELLY CORPORATION (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001027690-A2 | ELECTROCHROMIC DEVICE | UNIVERSITY COLLEGE DUBLIN (IE) | 2001-04-19 | — | — | WO | disclosed |
| US-5724187-A | FOR A MOTOR VEHICLE | DONNELLY CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5668663-A | ELEMENT COMPOSED OF A SOLID FILM AND AN ELECTROLYTE COMPRISING REDOX REACTION PROMOTERS AND ALKALI IONS AND/OR PROTONS | DONNELLY CORPORATION (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0758929-A4 | ELECTROCHROMIC MIRRORS AND DEVICES | DONNELLY CORP (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0758929-A1 | ELECTROCHROMIC MIRRORS AND DEVICES | DONNELLY CORPORATION (US) | 1997-02-26 | — | — | EP | disclosed |
| WO-1995030495-A1 | ELECTROCHROMIC MIRRORS AND DEVICES | DONNELLY CORPORATION (US) | 1995-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168086-A1 | NOVEL CROSS-LINKER FOR THE PREPARATION OF A NEW FAMILY OF SINGLE ION CONDUCTION POLYMERS FOR ELECTROCHEMICAL DEVICES AND SUCH POLYMERS | PPOX, PFAS, LPO | PPARG 1478/4885LMNA 1965/4885NFE2L2 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.