Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670224 | 1.00 | GSK3B (0.41) | GSK3BDYRK1ACPT1ACYP11B1CYP11B2 | |
| SCHEMBL19365398 | 0.87 | PRMT5 (0.40) | GSK3BDYRK1AMEN1HTTKMT2A | |
| SCHEMBL19365399 | 0.87 | PRMT5 (0.40) | GSK3BDYRK1AMEN1HTTKMT2A | |
| SCHEMBL19365582 | 0.87 | GSK3B (0.39) | GSK3BDYRK1ACHRM4ABL1MEN1 | |
| SCHEMBL19670325 | 0.87 | GSK3B (0.39) | GSK3BDYRK1ACHRM4ABL1MEN1 | |
| SCHEMBL19365792 | 0.86 | MEN1 (0.38) | GSK3BDYRK1ACPT1ACYP11B1CYP11B2 | |
| SCHEMBL17618603 | 0.85 | GSK3B (0.40) | GSK3BDYRK1ACPT1AGPR6CHRM4 | |
| SCHEMBL19670317 | 0.85 | DYRK1A (0.42) | GSK3BDYRK1ACYP11B1CYP11B2CTPS1 | |
| SCHEMBL19365296 | 0.85 | DYRK1A (0.42) | GSK3BDYRK1ACYP11B1CYP11B2CTPS1 | |
| SCHEMBL19365403 | 0.85 | PIK3C3 (0.42) | GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |