Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365582 | 1.00 | GSK3B (0.39) | GSK3BDYRK1AABL1JAK2NTRK1 | |
| SCHEMBL19670319 | 0.91 | FAAH (0.42) | GSK3BDYRK1AJAK2NTRK1TRPV1 | |
| SCHEMBL19364826 | 0.91 | FAAH (0.42) | GSK3BDYRK1AJAK2NTRK1TRPV1 | |
| SCHEMBL19365398 | 0.90 | PRMT5 (0.40) | GSK3BDYRK1ANTRK1MEN1HTT | |
| SCHEMBL19365399 | 0.90 | PRMT5 (0.40) | GSK3BDYRK1ANTRK1MEN1HTT | |
| SCHEMBL19365792 | 0.88 | MEN1 (0.38) | GSK3BDYRK1AABL1TRPV1MEN1 | |
| SCHEMBL19365301 | 0.87 | GSK3B (0.41) | GSK3BDYRK1AABL1MEN1HTT | |
| SCHEMBL19670317 | 0.87 | DYRK1A (0.42) | GSK3BDYRK1ACYP3A4 | |
| SCHEMBL19365296 | 0.87 | DYRK1A (0.42) | GSK3BDYRK1ACYP3A4 | |
| SCHEMBL19670224 | 0.87 | GSK3B (0.41) | GSK3BDYRK1AABL1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |