SCHEMBL19366132

SCHEMBL19366132

Cn1nc(-c2c(F)cccc2F)nc1C(=O)NS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
LGALS8 O00214 1/20 0.38
LGALS3 P17931 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
FBP1 P09467 1/20 0.37
KAT6A Q92794 2/20 0.37
ALDH1A1 P00352 2/20 0.36
CCR4 P51679 3/20 0.36
PTGER3 P43115 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22427993 0.88 KAT6A (0.45) POLBFBP1KAT6ACA12CA1
SCHEMBL19366134 0.87 KAT6A (0.39) POLBKAT6A
SCHEMBL22427962 0.85 KAT6A (0.47) KAT8FBP1KAT6ACCR4PTGER3
SCHEMBL22427937 0.85 FBP1 (0.44) FLT1FLT4KDRLGALS8LGALS3
SCHEMBL22427810 0.82 POLB (0.43) POLBFLT1FLT4KDRKAT8
SCHEMBL22428266 0.80 POLB (0.41) POLBFLT1FLT4KDRKAT8
SCHEMBL21317103 0.79 FLT1 (0.45) POLBFLT1FLT4KDRLGALS8
SCHEMBL22427841 0.77 POLB (0.42) POLBFLT1FLT4KDRLGALS8
SCHEMBL22428306 0.77 POLB (0.42) POLBFLT1FLT4KDRLGALS8
SCHEMBL22427846 0.77 POLB (0.42) POLBFLT1FLT4KDRKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 US disclosed
WO-2017157735-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM POLB 4665/4885FLT1 4843/4885FLT4 4873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.