SCHEMBL19366134

SCHEMBL19366134

Cn1nc(-c2c(F)cccc2F)nc1C(=O)NS(=O)(=O)c1ccccc1Br

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 17/20 0.39
POLB P06746 1/20 0.34
CYSLTR2 Q9NS75 1/20 0.34
CYSLTR1 Q9Y271 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22427993 0.88 KAT6A (0.45) KAT6APOLB
SCHEMBL19366132 0.87 POLB (0.42) KAT6APOLB
SCHEMBL22427962 0.85 KAT6A (0.47) KAT6ACYSLTR1
SCHEMBL22427880 0.82 POLB (0.39) KAT6APOLB
SCHEMBL19366171 0.80 POLB (0.35) KAT6APOLB
SCHEMBL21668023 0.78 KAT6A (0.36) KAT6APOLB
SCHEMBL22427937 0.77 FBP1 (0.44) KAT6A
SCHEMBL22428160 0.77 POLB (0.36) KAT6APOLB
SCHEMBL22427691 0.77 PTGS1 (0.37) KAT6APOLB
SCHEMBL22428294 0.76 KMT2A (0.40) KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 US disclosed
WO-2017157735-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM KAT6A 2821/4885POLB 4665/4885CYSLTR2 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.