Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 8/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821035 | 0.85 | PIN1 (0.49) | PIN1HCAR2CYP1A2MAPK1CASP1 | |
| SCHEMBL22428057 | 0.77 | SLC9A1 (0.47) | PIN1SLC9A1SMPD3 | |
| SCHEMBL19357016 | 0.75 | HCAR2 (0.43) | PIN1SLC9A1HCAR2CYP1A2MAPK1 | |
| SCHEMBL22427871 | 0.72 | SLC9A1 (0.45) | PIN1SLC9A1 | |
| SCHEMBL22427715 | 0.71 | POLB (0.42) | SLC9A1 | |
| SCHEMBL6469854 | 0.70 | HCAR2 (0.44) | PIN1HCAR2CYP2C19 | |
| SCHEMBL5552730 | 0.69 | KDM4E (0.43) | PIN1SLC9A1CYP1A2MAPK1CASP1 | |
| SCHEMBL6494249 | 0.66 | HCAR2 (0.43) | PIN1HCAR2RNASEH1 | |
| SCHEMBL22479903 | 0.66 | PIN1 (1.00) | PIN1SLC9A1CYP1A2MAPK1CASP1 | |
| SCHEMBL1398894 | 0.66 | HCRTR1 (0.44) | PIN1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200288710-A1 | SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-09-17 | — | — | US | disclosed |
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200288710-A1 | SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS | DDT, MPST, STOM | PIN1 2507/4885SLC9A1 1734/4885HCAR2 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.