SCHEMBL19366171

SCHEMBL19366171

Cc1c(-c2c(F)cccc2F)nc(C(=O)NS(=O)(=O)c2ccccc2Br)n1C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
KAT6A Q92794 10/20 0.35
EDNRA P25101 3/20 0.34
EDNRB P24530 2/20 0.34
WNT3A P56704 1/20 0.34
FBP1 P09467 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21668023 0.95 KAT6A (0.36) POLBKAT6AEDNRAEDNRBWNT3A
SCHEMBL22428161 0.89 KAT6A (0.45) POLBKAT6AFBP1
SCHEMBL22428266 0.88 POLB (0.41) POLBFBP1
SCHEMBL22428294 0.87 KMT2A (0.40) KAT6A
SCHEMBL19366174 0.86 KAT6A (0.47) KAT6AFBP1
SCHEMBL22428160 0.82 POLB (0.36) POLBKAT6AEDNRAEDNRBWNT3A
SCHEMBL19366134 0.80 KAT6A (0.39) POLBKAT6A
SCHEMBL22427880 0.79 POLB (0.39) POLBKAT6AEDNRAEDNRBWNT3A
SCHEMBL22427691 0.78 PTGS1 (0.37) POLBKAT6AEDNRAEDNRB
SCHEMBL22427983 0.78 POLB (0.38) POLBKAT6AEDNRAEDNRBFBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 US disclosed
WO-2017157735-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM POLB 4665/4885KAT6A 2821/4885EDNRA 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.