SCHEMBL19366174

SCHEMBL19366174

COc1ccccc1S(=O)(=O)NC(=O)c1nc(-c2c(F)cccc2F)c(C)n1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 2/20 0.47
FBP1 P09467 3/20 0.39
KAT8 Q9H7Z6 1/20 0.39
PTGER4 P35408 1/20 0.39
BRD4 O60885 1/20 0.38
BRD1 O95696 1/20 0.38
BRPF1 P55201 1/20 0.38
ACLY P53396 1/20 0.37
SLC40A1 Q9NP59 1/20 0.37
PTGER3 P43115 1/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ITGAV P06756 1/20 0.35
LTC4S Q16873 1/20 0.35
GAA P10253 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22428161 0.88 KAT6A (0.45) KAT6AFBP1PTGER4SLC40A1ALDH1A1
SCHEMBL22428003 0.87 KAT6A (0.47) KAT6AKAT8PTGER4ACLYSLC40A1
SCHEMBL22428266 0.86 POLB (0.41) FBP1KAT8PTGER3SMN1; SMN2ALDH1A1
SCHEMBL19366171 0.86 POLB (0.35) KAT6AFBP1
SCHEMBL22427727 0.82 FBP1 (0.47) KAT6AFBP1KAT8SMN1; SMN2GAA
SCHEMBL21668023 0.81 KAT6A (0.36) KAT6AFBP1
SCHEMBL22427962 0.81 KAT6A (0.47) KAT6AFBP1KAT8PTGER4ACLY
SCHEMBL22427690 0.79 KAT6A (0.47) KAT6AFBP1KAT8PTGER4BRD4
SCHEMBL22427844 0.75 KAT6A (0.44) KAT6AFBP1KAT8PTGER4PTGER3
SCHEMBL22427891 0.75 KAT6A (0.45) KAT6AFBP1PTGER4GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 US disclosed
WO-2017157735-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM KAT6A 2821/4885FBP1 378/4885KAT8 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.