SCHEMBL19366192

SCHEMBL19366192

CC(=O)Nc1ccc(C(C)C)c(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 6/20 0.60
▸ GAA P10253 1/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.51
▸ ESRRA P11474 1/20 0.50
▸ ALDH1A1 P00352 3/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ NPC1 O15118 1/20 0.46
▸ MAOA P21397 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ EPHX1 P07099 1/20 0.46
▸ EPHX2 P34913 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879857 0.86 GAA (0.59) RORCGAASMN1; SMN2ESRRAALDH1A1
SCHEMBL2123696 0.86 EPHX1 (0.46) RORCSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL9633496 0.83 SMN1; SMN2 (0.47) RORCSMN1; SMN2MAPTEPHX1EPHX2
SCHEMBL10673457 0.82 RORC (0.42) RORCSMN1; SMN2MEN1MAPTKMT2A
SCHEMBL10521379 0.82 CYP3A4 (0.69) SMN1; SMN2ESRRAALDH1A1MEN1MAPT
SCHEMBL11266713 0.82 APEX1 (0.69) MEN1KMT2A
SCHEMBL22059614 0.81 CYP1A2 (0.50) RORCGAASMN1; SMN2MEN1MAPT
SCHEMBL14199943 0.81 GAA (0.56) RORCGAASMN1; SMN2ALDH1A1MEN1
SCHEMBL6811107 0.81 ALDH1A1 (0.56) RORCGAAALDH1A1MEN1MAPT
SCHEMBL10520043 0.80 KMT2A (0.62) SMN1; SMN2ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 — — US disclosed
EP-3429355-B1 SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS BAYER CROPSCIENCE AG (DE) 2020-02-05 — — EP disclosed
WO-2017157735-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM RORC 4839/4885GAA 697/4885SMN1; SMN2 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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