Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911275 | 0.88 | MAPT (0.59) | MAPTMAOAMAOBPTPN1ESR2 | |
| SCHEMBL900953 | 0.79 | MAPT (0.70) | MAPTMAOAMAOBPTPN1ESR2 | |
| SCHEMBL1237586 | 0.75 | MAPT (0.70) | MAPTMAOAMAOBPTPN1PTPRC | |
| SCHEMBL3397911 | 0.73 | MAPT (0.62) | MAPTMAOAMAOBPTPN1PTPRC | |
| SCHEMBL1235852 | 0.73 | MAPT (0.68) | MAPTMAOAMAOBPTPN1PTPRC | |
| SCHEMBL1021060 | 0.72 | MAPT (0.56) | MAPTMAOAMAOBPTPN1PTPRC | |
| SCHEMBL1238056 | 0.71 | MAPT (0.55) | MAPTMAOAMAOBPTPN1PTPRC | |
| SCHEMBL11181983 | 0.71 | MAPT (0.65) | MAPTMAOAMAOBPTPN1ESR2 | |
| SCHEMBL2205029 | 0.71 | MAPT (0.64) | MAPT | |
| SCHEMBL28640995 | 0.68 | MAPT (0.37) | MAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260043010-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2026-02-12 | — | — | US | disclosed |
| US-12371674-B2 | Enone reductases | CODEXIS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20210324344-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2021-10-21 | — | — | US | disclosed |
| US-10995321-B2 | Enone reductases | CODEXIS, INC. (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200040311-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2020-02-06 | — | — | US | disclosed |
| US-20180312815-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-11-01 | — | — | US | disclosed |
| CN-105754099-B | Composition and polymer | 旭化成株式会社 | 2018-09-18 | — | — | CN | disclosed |
| US-10035988-B2 | Enone reductases | CODEXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170175087-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-22 | — | — | US | disclosed |
| US-9617568-B2 | Enone reductases | CODEXIS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20150031095-A1 | ENONE REDUCTASES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-01-29 | — | — | US | disclosed |
| US-8883475-B2 | Enone reductases | CODEXIS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20130115663-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-8329438-B2 | Enone reductases | CODEXIS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2382308-A2 | ENONE REDUCTASES | Codexis, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20100190218-A1 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2010075574-A2 | ENONE REDUCTASES | CODEXIS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| EP-1191008-B1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6746728-B1 | SUPERIOR LIQUID CRYSTALLINITY AND CO-SOLUBILITY WITH CURRENTLY USED LIQUID CRYSTAL COMPOUNDS; TEMPERATURE RANGE OVER WHICH LIQUID CRYSTALLINITY IS SHOWN IS BROAD; THRESHOLD VOLTAGE IS LOW; CAPABLE OF HIGH SPEED RESPONSE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1191008-A1 | COMPOUND HAVING TETRAHYDRONAPHTHALENE SKELETON AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312815-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | MAPT 4492/4885MAOA 1434/4885MAOB 1135/4885 |
| US-10995321-B2 | Enone reductases | ENO1, DCXR, RRM2B | MAPT 4492/4885MAOA 1434/4885MAOB 1135/4885 |
| US-20200040311-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | MAPT 4492/4885MAOA 1434/4885MAOB 1135/4885 |
| US-12371674-B2 | Enone reductases | ENO1, DCXR, RRM2B | MAPT 4492/4885MAOA 1434/4885MAOB 1135/4885 |
| US-20260043010-A1 | ENONE REDUCTASES | DCXR, ENY2, UPF1 | MAPT 4465/4885MAOA 1498/4885MAOB 1033/4885 |
| US-20210324344-A1 | ENONE REDUCTASES | ENO1, DCXR, RRM2B | MAPT 4492/4885MAOA 1434/4885MAOB 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.