Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14700300 | 0.89 | YTHDC1 (0.41) | SLC6A2SLC6A4SLC6A3YTHDC1HDAC8 | |
| SCHEMBL14700327 | 0.83 | YTHDC1 (0.38) | SLC6A2SLC6A4SLC6A3YTHDC1HDAC8 | |
| SCHEMBL19370544 | 0.82 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL14700308 | 0.73 | PTPN1 (0.49) | — | |
| SCHEMBL14700304 | 0.70 | MEP1B (0.44) | — | |
| SCHEMBL14700301 | 0.70 | HDAC8 (0.37) | YTHDC1HDAC8HDAC6FFAR1CYP1A2 | |
| SCHEMBL19370699 | 0.69 | PTPN1 (0.41) | SLC6A2SLC6A4SLC6A3CETPCYP2C19 | |
| SCHEMBL14700257 | 0.69 | CRHBP (0.42) | SLC6A2SLC6A4SLC6A3CETPCYP2C19 | |
| SCHEMBL14700329 | 0.69 | PTPN1 (0.56) | HDAC6 | |
| SCHEMBL14700290 | 0.69 | SMN1; SMN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2557072-B1 | PARA- OR MESO-FUNCTIONALIZED AROMATIC KETONE COMPOUNDS, PREPARATION METHODS THEREOF, AND PHOTOPOLYMERIZATION INITIATORS COMPRISING THE SAME | SHENZHEN UV-CHEMTECH CO LTD (CN) | 2017-09-20 | — | — | EP | disclosed |