Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.31 |
| ▸ | MAPT | P10636 | 6/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223306 | 0.79 | CUL4A (0.41) | HSD17B10KDM4EHPGDGAACUL4A | |
| SCHEMBL17630210 | 0.79 | — | — | |
| SCHEMBL4454393 | 0.73 | — | — | |
| SCHEMBL17630170 | 0.70 | ALDH1A1 (0.35) | HSD17B10KDM4EHPGDGAACUL4A | |
| SCHEMBL6223351 | 0.70 | ALAD (0.50) | KDM4EGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL234370 | 0.69 | CTPS1 (0.42) | HSD17B10KDM4EHPGDGAAALDH1A1 | |
| SCHEMBL6594701 | 0.68 | KDM4E (0.49) | HSD17B10KDM4EHPGDGAAALDH1A1 | |
| SCHEMBL8777826 | 0.68 | CYP19A1 (0.40) | HSD17B10KDM4EHPGDGAAALDH1A1 | |
| SCHEMBL17630168 | 0.68 | KDM4E (0.37) | HSD17B10KDM4EHPGDGAACUL4A | |
| Bromide SCHEMBL17201605 | 0.68 | CTPS1 (0.41) | HSD17B10KDM4EHPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197891-B1 | FACTOR XIA-INHIBITING PYRIDOBENZAZEPINE AND PYRIDOBENZAZOCINE DERIVATIVES | Bayer Pharma AG (DE) | 2018-11-21 | — | — | EP | disclosed |
| EP-1910330-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED THIAZOLES, PYRROLES AND THIOPHENES | AICURIS GMBH & CO KG (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| EP-1910330-A1 | HETEROCYCLYLAMIDE-SUBSTITUTED THIAZOLES, PYRROLES AND THIOPHENES | Bayer HealthCare AG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009578-A1 | HETEROCYCLYLAMIDE-SUBSTITUTED THIAZOLES, PYRROLES AND THIOPHENES | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |