Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767621 | 0.72 | KDM4E (0.70) | KDM4EMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL6223306 | 0.70 | CUL4A (0.41) | KDM4EMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL4607222 | 0.70 | KMT2A (0.46) | KDM4EHSD17B10KMT2ACYP1A2CYP2C9 | |
| SCHEMBL10872998 | 0.69 | KMT2A (0.40) | KDM4ELMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL2482717 | 0.69 | CUL4A (0.45) | KDM4EMAPK1LMNAMAPTKMT2A | |
| SCHEMBL4608245 | 0.69 | CYP1A2 (0.48) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7565510 | 0.69 | RAB9A (0.71) | KDM4EMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL1937060 | 0.68 | HSD17B10 (0.33) | KDM4EMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL10791960 | 0.68 | KDM4E (0.64) | KDM4EMAPK1HSD17B10LMNAMAPT | |
| SCHEMBL11790359 | 0.68 | RAB9A (0.65) | KDM4EMAPK1HSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927192-B1 | MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-12 | — | — | EP | disclosed |