Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370709 | 0.82 | TDP1 (0.41) | KMT2AF2F10TDP1 | |
| SCHEMBL24114275 | 0.80 | KMT2A (0.43) | MEN1KMT2AF2F10TDP1 | |
| SCHEMBL22317081 | 0.80 | KMT2A (0.40) | MEN1KMT2AF2F10TDP1 | |
| SCHEMBL2559106 | 0.79 | MEN1 (0.45) | MEN1KMT2AGAA | |
| SCHEMBL22844028 | 0.79 | P2RX7 (0.41) | MEN1KMT2AF2F10TDP1 | |
| SCHEMBL26023730 | 0.78 | KMT2A (0.35) | MEN1KMT2AGAA | |
| SCHEMBL23964063 | 0.77 | NPC1 (0.39) | KMT2AF2F10TDP1 | |
| SCHEMBL12376720 | 0.77 | F2 (0.57) | MEN1KMT2AF2TDP1 | |
| SCHEMBL19676845 | 0.76 | ADRA1D (0.42) | MEN1KMT2ATDP1 | |
| SCHEMBL20777519 | 0.75 | HPGD (0.43) | MEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161119-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2017-09-21 | — | — | WO | disclosed |