Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24326661 | 0.80 | KDM4E (0.34) | KMT2AHPGDKDM4EATMHDAC6 | |
| SCHEMBL12287113 | 0.80 | TP53 (0.50) | KMT2AMEN1HPGDTP53ALDH1A1 | |
| SCHEMBL19370673 | 0.78 | MEN1 (0.48) | KMT2AMEN1GAA | |
| SCHEMBL21949741 | 0.77 | KMT2A (0.38) | KMT2AMEN1HPGDTP53ALDH1A1 | |
| SCHEMBL24083692 | 0.77 | GAA (0.52) | KMT2AHPGDTP53ALDH1A1MAPT | |
| SCHEMBL19676845 | 0.76 | ADRA1D (0.42) | KMT2AMEN1HPGDTP53ALDH1A1 | |
| SCHEMBL25003658 | 0.76 | MLYCD (0.50) | KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL1647150 | 0.76 | MEN1 (0.52) | KMT2AMEN1HPGDTP53ALDH1A1 | |
| SCHEMBL20777519 | 0.75 | HPGD (0.43) | KMT2AMEN1HPGDTP53ALDH1A1 | |
| SCHEMBL18900760 | 0.74 | HDAC6 (0.40) | KMT2AMEN1HPGDTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |