Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677438 | 1.00 | HSD17B10 (0.53) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL1937493 | 0.98 | HSD17B10 (0.51) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL25107807 | 0.96 | HSD17B10 (0.49) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL19642427 | 0.92 | MAOA (0.55) | HSD17B10ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2400184 | 0.91 | PRKDC (0.51) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL2436551 | 0.89 | ALDH1A1 (0.47) | HSD17B10ERCC1DNASE1FEN1ERCC4 | |
| SCHEMBL24518077 | 0.89 | ALDH1A1 (0.48) | HSD17B10ALDH1A1MEN1MAPTALOX15 | |
| SCHEMBL1938064 | 0.86 | SLC16A3 (0.51) | ALDH1A1MEN1MAPTKMT2APRKDC | |
| SCHEMBL15992772 | 0.85 | CHRNA7 (0.49) | ALDH1A1MEN1MAPTKMT2AXDH | |
| SCHEMBL12298174 | 0.85 | MAPT (0.56) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2011-09-01 | — | — | US | disclosed |
| EP-2331520-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | Cancer Research Initiative Foundation (MY) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010033011-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | CANCER RESEARCH INITIATIVES FOUNDATION (MY) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212955-A1 | ROSAMINE DERIVATIVES AS AGENTS FOR THE TREATMENT OF CANCER | LTB4R, LTB4R2, NR1H3 | HSD17B10 454/4885ERCC1 1354/4885DNASE1 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.