Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157106 | 1.00 | ALOX12 (0.41) | ALOX12KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2592464 | 1.00 | ALOX12 (0.41) | ALOX12KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2591286 | 0.85 | KMT2A (0.34) | KDM4EMEN1KMT2AMAPTHTT | |
| SCHEMBL1935692 | 0.84 | PIM1 (0.39) | MEN1KMT2AMAPTARGABRP | |
| SCHEMBL14627192 | 0.83 | AR (0.41) | MEN1KMT2AHTTTSHRAR | |
| SCHEMBL22545512 | 0.77 | KDM4E (0.41) | KDM4EMEN1KMT2AMAPTHTT | |
| SCHEMBL22531360 | 0.77 | NR4A1 (0.48) | KDM4EMEN1KMT2AARHPGD | |
| SCHEMBL29471973 | 0.77 | NR4A1 (0.48) | KDM4EMEN1KMT2AARHPGD | |
| SCHEMBL1415184 | 0.76 | GABRP (0.44) | MEN1KMT2AHTTTSHRLMNA | |
| SCHEMBL4115038 | 0.75 | CYP1A2 (0.45) | KDM4EMEN1KMT2AARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| CN-102131804-B | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2014-12-03 | — | — | CN | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| CN-102131804-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2011-07-20 | — | — | CN | disclosed |
| EP-2331536-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, CHRM5 | ALOX12 3219/4885KDM4E 2816/4885MEN1 931/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | ALOX12 3042/4885KDM4E 2708/4885MEN1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.