Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627192 | 0.87 | AR (0.41) | CA1CA2ARGABRPGABRD | |
| SCHEMBL2592464 | 0.84 | ALOX12 (0.41) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL12157106 | 0.84 | ALOX12 (0.41) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1937149 | 0.84 | ALOX12 (0.41) | ARGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL97166 | 0.83 | MEN1 (0.41) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL3897604 | 0.82 | PIM1 (0.53) | PIM1PIM3ERN1TLR2TLR1 | |
| SCHEMBL20797216 | 0.81 | PDK1 (0.37) | PIM1PIM3ERN1TLR2TLR1 | |
| SCHEMBL27880238 | 0.81 | RAB9A (0.37) | PIM1PIM3ERN1TLR2TLR1 | |
| SCHEMBL2947290 | 0.81 | ERN1 (0.39) | PIM1PIM3ERN1TLR2TLR1 | |
| SCHEMBL2591286 | 0.80 | KMT2A (0.34) | ARGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2331536-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, CHRM5 | PIM1 4654/4885PIM3 4630/4885ERN1 1873/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | PIM1 4569/4885PIM3 4566/4885ERN1 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.