SCHEMBL6129786

SCHEMBL6129786

NNc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 13/20 0.46
CA9 Q16790 13/20 0.46
CA2 P00918 11/20 0.46
CA7 P43166 6/20 0.46
CA1 P00915 6/20 0.46
KDM4E B2RXH2 2/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
BCHE P06276 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
KMT2A Q03164 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
PDE7A Q13946 1/20 0.37
PDE7B Q9NP56 1/20 0.37
RET P07949 2/20 0.34
GRK5 P34947 2/20 0.34
TYRO3 Q06418 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5679686 0.80 CA12 (0.40) CA12CA9CA2CA7CA1
SCHEMBL11387847 0.79 KMT2A (0.46) CA12CA9CA2CA7CA1
SCHEMBL3257815 0.78 ALDH1A1 (0.54) CA12CA9CA2CA7CA1
SCHEMBL193750 0.77 CA12 (0.50) CA12CA9CA2CA7CA1
SCHEMBL2288532 0.73 KMT2A (0.38) CA12CA9CA2CA7CA1
SCHEMBL9179277 0.73 RET (0.53) CA12CA9CA2CA7CA1
SCHEMBL995389 0.73 CA12 (0.50) CA12CA9CA2CA7CA1
SCHEMBL3259642 0.73 CA1 (0.50) CA12CA9CA2CA7CA1
SCHEMBL230481 0.73 CA9 (0.50) CA12CA9CA2CA7CA1
SCHEMBL1463156 0.73 CA9 (0.50) CA12CA9CA2CA7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310503-A4 PROCESS FOR PRODUCING HYDRAZINOMONOSACCHARIDE DERIVATIVES AND USE THEREOF TAKARA BIO INC (JP) 2005-10-05 EP disclosed
US-6916920-B2 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2005-07-12 US disclosed
US-6916920-B2 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2005-07-12 US disclosed
US-6916920-B2 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2005-07-12 US disclosed
US-20040006221-A1 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2004-01-08 US disclosed
US-20040006221-A1 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2004-01-08 US disclosed
US-20040006221-A1 Process for producing hydrazinomonosaccharide derivatives and use thereof TAKARA BIO INC. (JP) 2004-01-08 US disclosed
EP-1310503-A1 PROCESS FOR PRODUCING HYDRAZINOMONOSACCHARIDE DERIVATIVES AND USE THEREOF TAKARA BIO INC. (JP) 2003-05-14 EP disclosed
EP-1310503-A1 PROCESS FOR PRODUCING HYDRAZINOMONOSACCHARIDE DERIVATIVES AND USE THEREOF TAKARA BIO INC. (JP) 2003-05-14 EP disclosed
WO-2002012254-A1 PROCESS FOR PRODUCING HYDRAZINOMONOSACCHARIDE DERIVATIVES AND USE THEREOF TAKARA BIO INC. (JP) 2002-02-14 WO disclosed
US-4021542-A Derivatives of hydrazino-monosaccharides and aldohexoses which are useful as intermediates for preparing compounds or as compounds which lower the uric acid BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-05-03 US disclosed