Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.46 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 17/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375187 | 0.84 | TRPC4 (0.44) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL19375493 | 0.78 | ALDH1A1 (0.38) | TRPC4TRPC5KCNH2P2RX3 | |
| SCHEMBL19375494 | 0.77 | TRPC4 (0.43) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL19375568 | 0.77 | TRPC4 (0.43) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL19375117 | 0.75 | PDE5A (0.36) | TRPC4TRPC5KCNH2TRPC1TSHR | |
| SCHEMBL21345327 | 0.74 | TRPC5 (0.50) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL21332680 | 0.74 | TRPC5 (0.47) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL21332508 | 0.74 | TRPC5 (0.47) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL21344908 | 0.74 | TRPC5 (0.47) | TRPC4TRPC5KCNH2TRPC1P2RX3 | |
| SCHEMBL30642085 | 0.74 | TRPC5 (0.47) | TRPC4TRPC5KCNH2TRPC1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |