Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218867 | 0.82 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL23529356 | 0.80 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL6736049 | 0.80 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL2118284 | 0.80 | ATM (0.55) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7036575 | 0.80 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL9557865 | 0.79 | ATM (0.48) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL3268354 | 0.79 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL26054320 | 0.79 | ATM (0.58) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL1483376 | 0.79 | ALDH1A1 (0.55) | LMNASMN1; SMN2HTTMAPTKMT2A | |
| SCHEMBL27938343 | 0.79 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |
| EP-0245835-B1 | NOVEL THIOPHENE DERIVATIVES AND METHODS FOR PRODUCING THE SAME | SEITETSU KAGAKU CO., LTD. (JP) | 1993-05-05 | — | — | EP | claimed |
| JP-8092239-A | — | — | None | — | — | JP | disclosed |
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| WO-2016150937-A1 | METHOD FOR PREPARATION OF THIOPHENECARBONYL CHLORIDES | LONZA LTD (CH) | 2016-09-29 | — | — | WO | disclosed |
| US-8530646-B2 | Oxazolidinone derivative having 7-membered hetero ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | BAYERCROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | EMORY UNIVERSITY | 2008-09-11 | — | — | US | disclosed |
| WO-2007033080-A2 | ALZHEIMER'S DISEASE IMAGING AGENTS | EMORY UNIVERSITY (US) | 2007-03-22 | — | — | WO | disclosed |
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0172031-B1 | NOVEL SULFENYLATED ACYLHYDRAZONES, COMPOSITIONS CONTAINING THEM, METHODS OF MAKING THEM AND THEIR USE | ROHM AND HAAS COMPANY (US) | 1988-05-18 | — | — | EP | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4695405-A | Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| CN-86105836-A | Hydrocarbylthionatedacylhydrazone acylhydrazone | — | 1987-03-04 | — | — | CN | disclosed |
| EP-0172031-A1 | Novel sulfenylated acylhydrazones, compositions containing them, methods of making them and their use | ROHM AND HAAS COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | TYMP, TYMS, TPMT | LMNA 4132/4885SMN1; SMN2 3041/4885HTT 1254/4885 |
| US-20080219922-A1 | Alzheimer's Disease Imaging Agents | APP, PSEN1, MAPT | LMNA 2871/4885SMN1; SMN2 1690/4885HTT 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.