Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | ULK1 | O75385 | 8/20 | 0.61 |
| ▸ | KIT | P10721 | 8/20 | 0.61 |
| ▸ | FLT3 | P36888 | 8/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.61 |
| ▸ | AURKA | O14965 | 3/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.61 |
| ▸ | IGF1R | P08069 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | PLK4 | O00444 | 2/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.61 |
| ▸ | PAK4 | O96013 | 2/20 | 0.61 |
| ▸ | ABL1 | P00519 | 2/20 | 0.61 |
| ▸ | INSR | P06213 | 2/20 | 0.61 |
| ▸ | FES | P07332 | 2/20 | 0.61 |
| ▸ | RET | P07949 | 2/20 | 0.61 |
| ▸ | MET | P08581 | 2/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511202 | 0.96 | KIT (0.62) | PTK2EGFRULK1KITFLT3 | |
| SCHEMBL1937645 | 0.83 | PRKCQ (0.65) | PTK2EGFRFLT3CHEK1NTRK1 | |
| SCHEMBL1937038 | 0.83 | ULK1 (0.63) | EGFRULK1PTK2BULK2 | |
| SCHEMBL1937715 | 0.81 | SYK (0.52) | EGFRFLT3AURKANTRK1MET | |
| SCHEMBL1937628 | 0.80 | ULK1 (0.60) | PTK2EGFRULK1KITFLT3 | |
| SCHEMBL17547570 | 0.80 | ULK1 (0.67) | ULK1KITFLT3CDK1ULK2 | |
| SCHEMBL2777601 | 0.80 | ULK1 (0.59) | ULK1FLT3ULK2 | |
| SCHEMBL1936755 | 0.80 | ULK1 (0.62) | ULK1ULK2 | |
| SCHEMBL24486552 | 0.79 | EGFR (0.81) | PTK2EGFRULK1SYKBTK | |
| SCHEMBL1936257 | 0.78 | ULK1 (0.61) | ULK1KITFLT3ULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245249-A1 | Heterocyclically Substituted Anilinopyrimidines | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| EP-2331533-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025850-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245249-A1 | Heterocyclically Substituted Anilinopyrimidines | POLL, H1-2, H1-0 | PTK2 3644/4885EGFR 2879/4885ULK1 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.