Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 19/20 | 0.59 |
| ▸ | ULK2 | Q8IYT8 | 5/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936257 | 0.88 | ULK1 (0.61) | ULK1ULK2FLT3 | |
| SCHEMBL17547570 | 0.82 | ULK1 (0.67) | ULK1ULK2FLT3 | |
| SCHEMBL1937038 | 0.80 | ULK1 (0.63) | ULK1ULK2 | |
| SCHEMBL1937627 | 0.80 | PTK2 (0.64) | ULK1ULK2FLT3 | |
| SCHEMBL1938235 | 0.78 | SYK (0.50) | ULK1 | |
| SCHEMBL1937628 | 0.78 | ULK1 (0.60) | ULK1ULK2FLT3 | |
| SCHEMBL2511202 | 0.78 | KIT (0.62) | ULK1ULK2FLT3 | |
| SCHEMBL17545176 | 0.77 | ULK1 (0.88) | ULK1ULK2FLT3 | |
| SCHEMBL1936755 | 0.77 | ULK1 (0.62) | ULK1ULK2 | |
| SCHEMBL24042601 | 0.76 | ULK1 (0.66) | ULK1ULK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025863-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |