Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.33 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377288 | 1.00 | HTR6 (0.43) | HTR6DRD2DRD3GHSRHTR2A | |
| SCHEMBL19377262 | 0.86 | HTR6 (0.43) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377160 | 0.84 | HTR6 (0.47) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377455 | 0.80 | HTR6 (0.45) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377425 | 0.80 | PNMT (0.49) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377427 | 0.80 | PNMT (0.49) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377457 | 0.80 | HTR6 (0.45) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19407062 | 0.73 | HTR6 (0.40) | HTR6DRD2DRD3HTR2AHTR2C | |
| SCHEMBL19377273 | 0.72 | IDH1 (0.54) | HTR6DRD2DRD3GHSRMEN1 | |
| SCHEMBL19377071 | 0.72 | MLNR (0.39) | HTR6DRD2DRD3GHSRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | claimed |
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | UTS2R, GHSR, GRPR | HTR6 231/4885DRD2 4443/4885DRD3 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.