Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | GCK | P35557 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313771 | 0.91 | HTT (0.51) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL17247214 | 0.88 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822844 | 0.88 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12769542 | 0.88 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL16621782 | 0.88 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL23957972 | 0.88 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL19382857 | 0.86 | ACACB (0.52) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL25841271 | 0.86 | ACACB (0.52) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL16250471 | 0.84 | HTT (0.61) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL20007864 | 0.84 | PTPN5 (0.46) | HTTSMN1; SMN2MMP14MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765176-B2 | Poly(ether ketone) polymers comprising cycloaliphatic units | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2017-09-19 | — | — | US | disclosed |