Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380417 | 0.91 | HTT (0.61) | HTTSMN1; SMN2TDP1L3MBTL1CNR2 | |
| SCHEMBL20007864 | 0.87 | PTPN5 (0.46) | HTTSMN1; SMN2PTPN5MMP14MMP2 | |
| SCHEMBL24795065 | 0.87 | MMP14 (0.45) | HTTSMN1; SMN2TDP1L3MBTL1PTPN5 | |
| SCHEMBL19383057 | 0.87 | MMP14 (0.45) | HTTSMN1; SMN2TDP1L3MBTL1PTPN5 | |
| SCHEMBL18407080 | 0.87 | PTPN5 (0.46) | HTTSMN1; SMN2PTPN5MMP14MMP2 | |
| SCHEMBL822791 | 0.86 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12769543 | 0.86 | HTT (0.67) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12200067 | 0.85 | HTT (0.55) | HTTSMN1; SMN2TDP1L3MBTL1CNR2 | |
| SCHEMBL13910298 | 0.85 | HTT (0.55) | HTTSMN1; SMN2TDP1L3MBTL1CNR2 | |
| SCHEMBL4548600 | 0.85 | HTT (0.55) | HTTSMN1; SMN2TDP1L3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200246761-A1 | NANOFILTRATION COMPOSITE MEMBRANES COMPRISING SELF-ASSEMBLED SUPRAMOLECULAR SEPARATION LAYER | BASF SE (DE) | 2020-08-06 | — | — | US | disclosed |