Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935247 | 0.79 | APOBEC3A (0.54) | APOBEC3AAPOBEC3G | |
| SCHEMBL19203822 | 0.68 | APOBEC3A (0.45) | APOBEC3AAPOBEC3G | |
| SCHEMBL2279042 | 0.65 | APOBEC3A (0.57) | APOBEC3AAPOBEC3G | |
| SCHEMBL18673022 | 0.63 | ALDH1A1 (0.46) | — | |
| SCHEMBL21515669 | 0.62 | APOBEC3A (0.49) | APOBEC3AAPOBEC3G | |
| SCHEMBL19171385 | 0.62 | — | — | |
| SCHEMBL15935240 | 0.60 | KDM4E (0.33) | — | |
| SCHEMBL19171675 | 0.60 | JAK2 (0.33) | — | |
| SCHEMBL2181213 | 0.60 | APOBEC3A (0.53) | APOBEC3AAPOBEC3G | |
| SCHEMBL22330381 | 0.60 | SSTR4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765068-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2017-09-19 | — | — | US | disclosed |