Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935247 | 0.83 | APOBEC3A (0.54) | APOBEC3AAPOBEC3GKDM4EMGLLHTR2A | |
| SCHEMBL30708692 | 0.74 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GKDM4EL3MBTL1LMNA | |
| SCHEMBL569917 | 0.73 | APOBEC3A (1.00) | APOBEC3AAPOBEC3GKDM4EL3MBTL1MGLL | |
| SCHEMBL21192994 | 0.72 | DYRK1A (0.47) | PDGFRBKITFGFR1BRAFPDGFRA | |
| SCHEMBL13995847 | 0.71 | APOBEC3A (0.73) | APOBEC3AAPOBEC3GKDM4EMGLLHTR2A | |
| SCHEMBL14249152 | 0.71 | APOBEC3A (0.73) | APOBEC3AAPOBEC3GKDM4EMGLLLMNA | |
| SCHEMBL22018908 | 0.71 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GHTR2AHTR2CPDE10A | |
| SCHEMBL4789376 | 0.71 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GHTR2AHTR2CPDE10A | |
| SCHEMBL21863369 | 0.71 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GHTR2AHTR2CPDE10A | |
| SCHEMBL1441278 | 0.71 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GKDM4EHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383624-B2 | Cargo delivery system and composition comprising the same | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-08-12 | — | — | US | claimed |
| EP-4107159-A1 | 5-(3-(ETHYLSULFONYL)PYRIDIN-2-YL)-PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDE AND INSECTICIDE AGENTS FOR CROP PROTECTION | PI Industries Ltd. (IN) | 2022-12-28 | — | — | EP | claimed |
| EP-2235020-A1 | PYRAZOLO [1,5-A] PYRIMIDINE COMPOUNDS | Wyeth LLC (US) | 2010-10-06 | — | — | EP | claimed |
| WO-2009086129-A1 | PYRAZOLO [1,5-A] PYRIMIDINE COMPOUNDS | WYETH (US) | 2009-07-09 | — | — | WO | claimed |
| EP-4107159-A1 | 5-(3-(ETHYLSULFONYL)PYRIDIN-2-YL)-PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDE AND INSECTICIDE AGENTS FOR CROP PROTECTION | PI Industries Ltd. (IN) | 2022-12-28 | — | — | EP | disclosed |
| EP-2523552-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS MARK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011087999-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS MARK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-21 | — | — | WO | disclosed |
| US-7514443-B2 | Substituted pyrazolo[1,5-a]pyrimidines as inhibitors of metabotropic glutamate receptors | HOFFMANN-LA ROCHE INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20080051421-A1 | Pyrazolo-pyridine | WICHMANN JUERGEN | 2008-02-28 | — | — | US | disclosed |
| US-7329662-B2 | Pyrazolo-pyridine | HOFFMANN-LA ROCHE INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20050130992-A1 | Pyrazolo-pyridine | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130992-A1 | Pyrazolo-pyridine | CHRM2, CHRM1, QDPR | APOBEC3A 2833/4885APOBEC3G 2904/4885KDM4E 1251/4885 |
| US-12383624-B2 | Cargo delivery system and composition comprising the same | ATG7, SQSTM1, BECN1 | APOBEC3A 4565/4885APOBEC3G 4482/4885KDM4E 3795/4885 |
| US-20080051421-A1 | Pyrazolo-pyridine | CHRM2, CHRM1, QDPR | APOBEC3A 2833/4885APOBEC3G 2904/4885KDM4E 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.