Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263716 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL19409835 | 0.82 | ALDH1A1 (0.81) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL31456224 | 0.82 | ALDH1A1 (0.81) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11279390 | 0.82 | ALDH1A1 (0.81) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11112478 | 0.82 | ALDH1A1 (0.81) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL10573762 | 0.81 | NPC1 (0.66) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL9506364 | 0.81 | ALDH1A1 (0.78) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL1363014 | 0.81 | TSHR (0.78) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL29838530 | 0.81 | ALDH1A1 (0.85) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11190753 | 0.80 | ALDH1A1 (0.70) | ALDH1A1TSHRGLATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| EP-3390355-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | Helsinn Healthcare S.A. (CH) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | ALDH1A1 793/4885TSHR 3317/4885GLA 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.