SCHEMBL1938436

SCHEMBL1938436

O=C(c1ccccc1)N(O)[C@@](O)(CO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DEPTOR Q8TB45 1/20 0.38
POLB P06746 1/20 0.37
CES1 P23141 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
RORC P51449 1/20 0.36
ADRA2C P18825 1/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25291595 1.00 SMN1; SMN2 (0.42) SMN1; SMN2RAB9AALDH1A1HPGDTDP1
SCHEMBL11119914 0.78 BLM (0.43) SMN1; SMN2RAB9AALDH1A1MAPTMEN1
SCHEMBL6180241 0.74 NPSR1 (0.39) SMN1; SMN2RAB9AALDH1A1TDP1L3MBTL1
SCHEMBL421668 0.74 NPSR1 (0.39) SMN1; SMN2RAB9AALDH1A1TDP1L3MBTL1
SCHEMBL1098842 0.72 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1HPGDTDP1L3MBTL1
SCHEMBL3679031 0.71 RIPK1 (0.42) SMN1; SMN2RAB9AALDH1A1L3MBTL1MEN1
SCHEMBL3280418 0.71 POLB (0.55) SMN1; SMN2ALDH1A1HPGDTDP1DEPTOR
SCHEMBL11262719 0.69 POLB (0.53) SMN1; SMN2ALDH1A1HPGDTDP1DEPTOR
SCHEMBL7684 0.69 CES1 (0.58) SMN1; SMN2ALDH1A1HPGDTDP1L3MBTL1
SCHEMBL414466 0.69 CES1 (0.58) SMN1; SMN2ALDH1A1HPGDTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9765294-B2 Chemically defined medium for the industrial scale culture of a species of Bordetella GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2017-09-19 US claimed
EP-3044308-B1 A CHEMICALLY DEFINED MEDIUM FOR THE INDUSTRIAL SCALE CULTURE OF A SPECIES OF BORDETELLA GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-08-09 EP claimed
US-20160222344-A1 A CHEMICALLY DEFINED MEDIUM FOR THE INDUSTRIAL SCALE CULTURE OF A SPECIES OF BORDETELLA GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2016-08-04 US claimed
EP-3044308-A1 A CHEMICALLY DEFINED MEDIUM FOR THE INDUSTRIAL SCALE CULTURE OF A SPECIES OF BORDETELLA GlaxoSmithKline Biologicals S.A. (BE) 2016-07-20 EP claimed
WO-2015036953-A1 A CHEMICALLY DEFINED MEDIUM FOR THE INDUSTRIAL SCALE CULTURE OF A SPECIES OF BORDETELLA GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) 2015-03-19 WO claimed
EP-2330897-A1 NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD The Trustees of Columbia University in the City of New York (US) 2011-06-15 EP claimed
WO-2010033847-A1 NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2010-03-25 WO claimed
US-12516089-B2 Bacteria based protein delivery T3 PHARMACEUTICALS AG (CH) 2026-01-06 US disclosed
US-20250368691-A1 Virulence Attenuated Bacteria Based Protein Delivery UNIV BASEL (CH) 2025-12-04 US disclosed
US-12358955-B2 Virulence attenuated bacteria based protein delivery UNIVERSITAET BASEL (CH) 2025-07-15 US disclosed
US-20240165265-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 US disclosed
US-20240165169-A1 Pharmaceutical Combinations for Treating Cancer T3 PHARMACEUTICALS AG (CH) 2024-05-23 US disclosed
CN-118006531-A Attenuated bacteria-based protein delivery 巴塞尔大学 2024-05-10 CN disclosed
EP-0983343-A1 E. COLI, SALMONELLA OR HAFNIA AUTOINDUCERS UNIVERSITY OF LEICESTER (GB) 2000-03-08 EP disclosed
WO-1998053047-A1 E. COLI, SALMONELLA OR HAFNIA AUTOINDUCERS UNIVERSITY OF LEICESTER (GB) 1998-11-26 WO disclosed
EP-0861321-A2 PHOSPHOPANTETHEINYL TRANSFERASES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-02 EP disclosed
WO-1997013845-A9 PHOSPHOPANTETHEINYL TRANSFERASES AND USES THEREOF 1997-08-14 WO disclosed
WO-1997013845-A2 PHOSPHOPANTETHEINYL TRANSFERASES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1997-04-17 WO disclosed
WO-1990011349-A1 VACCINES FOR COMBATTING SEPTICEMIC BACTERIA RHONE-MERIEUX S.A. (FR) 1990-10-04 WO disclosed
EP-0389347-A1 Vaccines against septicemic bacteria RHONE MERIEUX (FR) 1990-09-26 EP disclosed