Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421668 | 1.00 | NPSR1 (0.39) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL5669770 | 0.83 | ALDH1A1 (0.44) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL5669762 | 0.83 | ALDH1A1 (0.44) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL28831319 | 0.83 | — | — | |
| SCHEMBL6834107 | 0.81 | SMN1; SMN2 (0.47) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL25251559 | 0.79 | ALDH1A1 (0.40) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL14691647 | 0.75 | NPSR1 (0.44) | NPSR1KMT2ASMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL25291595 | 0.74 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL1938436 | 0.74 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1CYP3A4ALDH1A1 | |
| SCHEMBL3679031 | 0.74 | RIPK1 (0.42) | NPSR1KMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107921237-A | Sympathetic nerve cardiopulmonary neural modulation system and method | 反射医学公司 | 2018-04-17 | — | — | CN | disclosed |
| EP-1392317-A4 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA INC (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1392317-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | Antexpharma, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100327-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |