SCHEMBL19384366

SCHEMBL19384366

C[C](C)CC(=O)OCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
PNMT P11086 1/20 0.49
HTR2B P41595 2/20 0.39
HTR7 P34969 1/20 0.39
CYP1A2 P05177 1/20 0.38
ADRA2A P08913 1/20 0.38
MAOA P21397 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
DRD3 P35462 2/20 0.38
KDM4E B2RXH2 5/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 5/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 4/20 0.36
MEN1 O00255 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4059189 0.92 PNMT (0.54) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL4059193 0.88 PNMT (0.50) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL4839271 0.86 PNMT (0.51) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL8473291 0.86 PNMT (0.54) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL4064230 0.85 PNMT (0.45) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL5497718 0.85 PNMT (0.53) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL8474155 0.84 PNMT (0.51) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL6502789 0.83 PNMT (0.54) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL1830397 0.83 PNMT (0.57) RAB9ANPC1PNMTHTR2BHTR7
SCHEMBL6380799 0.83 PNMT (0.50) RAB9ANPC1PNMTHTR2BHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200061173-A1 IMMUNOGENIC COMPOSITION COMPRISING SURVIVIN PEPTIDES VAXEAL RESEARCH SAS (FR) 2020-02-27 US disclosed
EP-3432917-A1 IMMUNOGENIC COMPOSITION COMPRISING SURVIVIN PEPTIDES Vaxeal Research SAS (FR) 2019-01-30 EP disclosed
WO-2017162501-A1 IMMUNOGENIC COMPOSITION COMPRISING SURVIVIN PEPTIDES VAXEAL RESEARCH SAS (FR) 2017-09-28 WO disclosed