Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385394 | 0.71 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMAP2KMT2A | |
| SCHEMBL19385398 | 0.71 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMAP2KMT2A | |
| Potassium Ion SCHEMBL4337473 | 0.69 | MAP2 (0.46) | ALDH1A1KDM4EHPGDMAP2KMT2A | |
| Potassium Ion SCHEMBL5035169 | 0.69 | MAP2 (0.46) | ALDH1A1KDM4EHPGDMAP2KMT2A | |
| SCHEMBL19385396 | 0.64 | GAA (0.62) | ALDH1A1KDM4EHPGDPKMMAPT | |
| Carbazole SCHEMBL9576655 | 0.62 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| Carbazole SCHEMBL28021847 | 0.61 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL28197191 | 0.60 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAP2KMT2A | |
| Carbazole SCHEMBL8411559 | 0.60 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL2722021 | 0.59 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |