Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.54 |
| ▸ | TUBB | P07437 | 3/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385394 | 0.79 | KDM4E (0.51) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL19385398 | 0.79 | KDM4E (0.51) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2880010 | 0.78 | KDM4E (0.66) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL2345007 | 0.77 | KDM4E (0.61) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL3276393 | 0.76 | TUBB4A (0.67) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL7534562 | 0.76 | ALDH1A1 (0.71) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL29352308 | 0.76 | PKM (0.58) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL22443304 | 0.76 | PKM (0.58) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL4332747 | 0.75 | KDM4E (0.70) | GAAPKMKDM4EHTR6TUBB4A | |
| SCHEMBL2724382 | 0.75 | KDM4E (0.63) | GAAPKMKDM4EHTR6TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | claimed |
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |