Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385394 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19385396 | 0.79 | GAA (0.62) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL19400880 | 0.76 | ESR1 (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19385386 | 0.73 | MAPT (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28882768 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28245664 | 0.73 | KIF11 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL19385397 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL87871 | 0.71 | KDM4E (0.65) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30366683 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL29897041 | 0.71 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096360-A | Compositions and methods for treating or preventing inflammatory diseases, including type 10I and type II diabetes and thyroid diseases | 新概念医疗有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |