Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.35 |
| ▸ | KDM5C | P41229 | 3/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19426303 | 0.90 | TSHR (0.47) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL11616249 | 0.85 | TSHR (0.35) | TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL421346 | 0.79 | — | — | |
| SCHEMBL1720168 | 0.77 | — | — | |
| SCHEMBL10067112 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL11618480 | 0.76 | EPHX1 (0.36) | HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8568913 | 0.76 | MAPT (0.42) | TSHRLMNATDP1KDM4E | |
| SCHEMBL8603684 | 0.74 | TSHR (0.62) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL10435535 | 0.73 | — | — | |
| SCHEMBL11612026 | 0.72 | EPHX1 (0.42) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433259-B1 | CONJUGATES OF TACROLIMUS, THEIR COMPOSITIONS, AND THEIR USES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10913780-B2 | Conjugates, their compositions, their uses, and their methods of making | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2021-02-09 | — | — | US | disclosed |
| US-10913780-B2 | Conjugates, their compositions, their uses, and their methods of making | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2021-02-09 | — | — | US | disclosed |
| US-20190106473-A1 | CONJUGATES, THEIR COMPOSITIONS, THEIR USES, AND THEIR METHODS OF MAKING | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2019-04-11 | — | — | US | disclosed |
| US-20190106473-A1 | CONJUGATES, THEIR COMPOSITIONS, THEIR USES, AND THEIR METHODS OF MAKING | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2019-04-11 | — | — | US | disclosed |
| EP-3433259-A1 | CONJUGATES OF TACROLIMUS, THEIR COMPOSITIONS, AND THEIR USES | The Administrators of The Tulane Educational Fund (US) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017165607-A1 | CONJUGATES OF TACROLIMUS, THEIR COMPOSITIONS, AND THEIR USES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017165607-A1 | CONJUGATES OF TACROLIMUS, THEIR COMPOSITIONS, AND THEIR USES | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2017-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913780-B2 | Conjugates, their compositions, their uses, and their methods of making | INHA, INCENP, VIP | TSHR 3814/4885LMNA 1617/4885KMT2A 1310/4885 |
| US-20190106473-A1 | CONJUGATES, THEIR COMPOSITIONS, THEIR USES, AND THEIR METHODS OF MAKING | INHA, INCENP, VIP | TSHR 3814/4885LMNA 1617/4885KMT2A 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.