SCHEMBL19387271

SCHEMBL19387271

NC(=O)NC1C=CC(C(N)=O)=CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20348671 0.83
SCHEMBL17809660 0.76
SCHEMBL12574928 0.76 TSHR (0.33)
SCHEMBL13716521 0.75 NFKB1 (0.33)
SCHEMBL29686587 0.74 PIK3CD (0.33)
SCHEMBL12656700 0.73 GABRR1 (0.34) GABRR1
SCHEMBL29686766 0.72 CCNE1 (0.33)
SCHEMBL7563916 0.70 GABRR1 (0.32) GABRR1
SCHEMBL6277324 0.69 CYP2C9 (0.37)
SCHEMBL17733571 0.69 AURKA (0.32) GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11371996-B2 Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same WATERS TECHNOLOGIES CORPORATION (US) 2022-06-28 US disclosed
US-10436790-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2019-10-08 US disclosed
US-10416166-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2019-09-17 US disclosed
US-20180188259-A1 METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME WATERS TECHNOLOGIES CORPORATION (US) 2018-07-05 US disclosed
US-9772333-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATER TECHNOLOGIES CORPORATION (US) 2017-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10416166-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, CSGALNACT1 GABRR1 3621/4885
US-10436790-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, CSGALNACT1 GABRR1 3079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.