Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13830591 | 0.88 | QDPR (0.45) | ROCK2NAMPTBRD4CREBBPLMNA | |
| SCHEMBL30531024 | 0.85 | BRD4 (0.48) | HDAC1ROCK2NAMPTBRD4CREBBP | |
| SCHEMBL3509882 | 0.85 | BRD4 (0.48) | HDAC1ROCK2NAMPTBRD4CREBBP | |
| SCHEMBL15866724 | 0.84 | ACHE (0.49) | TPSAB1 | |
| SCHEMBL1668574 | 0.83 | ACKR3 (0.43) | NAMPTEGFR | |
| SCHEMBL14898051 | 0.83 | MEN1 (0.43) | ROCK2NAMPTBRD4CREBBPLMNA | |
| SCHEMBL12801527 | 0.83 | BCHE (0.45) | — | |
| SCHEMBL13835321 | 0.83 | BCHE (0.45) | — | |
| SCHEMBL25048390 | 0.83 | BRD4 (0.47) | ROCK2NAMPTBRD4CREBBPGLS | |
| SCHEMBL25358558 | 0.83 | GLS (0.48) | HDAC1ROCK2NAMPTBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |