Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188463 | 0.84 | PLA2G2A (0.61) | PLA2G2APLAUKMT2AMEN1TP53 | |
| SCHEMBL14812371 | 0.80 | PLA2G2A (0.57) | PLA2G2APLAUKMT2AMEN1 | |
| SCHEMBL23352165 | 0.74 | PLA2G2A (0.77) | PLA2G2AKMT2AMEN1TP53TSHR | |
| SCHEMBL10830829 | 0.73 | PLA2G2A (0.86) | PLA2G2AKMT2ATP53TSHRPLA2G4B | |
| SCHEMBL14536663 | 0.73 | L3MBTL1 (0.48) | PLA2G2APLAUKMT2AMEN1CYP19A1 | |
| SCHEMBL23352169 | 0.72 | PLA2G2A (0.96) | PLA2G2AKMT2ATP53TSHRPLA2G4B | |
| SCHEMBL17109507 | 0.71 | PLA2G2A (0.71) | PLA2G2AKMT2AMEN1TP53TSHR | |
| SCHEMBL2958348 | 0.71 | PLA2G2A (0.61) | PLA2G2APLAUKMT2AMEN1TP53 | |
| SCHEMBL4368371 | 0.71 | PARP10 (0.46) | PLA2G2APLAUKMT2AMEN1TSHR | |
| SCHEMBL2655120 | 0.70 | PLA2G2A (0.65) | PLA2G2AKMT2AMEN1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331561-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | Xenome Ltd (AU) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025510-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2010-03-11 | — | — | WO | disclosed |
| WO-2008077194-A1 | RECEPTOR AGONISTS | XENOME LTD (AU) | 2008-07-03 | — | — | WO | disclosed |